HIPEC (Hyperthermic Intraperitoneal Chemotherapy)

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is a specialized treatment used primarily for certain types of cancers that have spread to the peritoneal cavity (the space within the abdomen that contains the digestive organs). HIPEC combines chemotherapy with heat to target cancer cells more effectively.

Benefits of HIPEC:

• Localized Treatment: HIPEC targets cancer cells directly in the peritoneal cavity, potentially reducing the risk of recurrence compared to systemic chemotherapy alone.
• Enhanced Drug Penetration: The heat increases the permeability of cancer cells, allowing the chemotherapy drugs to penetrate more deeply and effectively.
• Improved Survival: For some patients, HIPEC can improve survival rates and disease control compared to standard treatments.

Indications for HIPEC:

HIPEC is used for specific cancers that have spread to the peritoneal cavity, including:

• Ovarian Cancer: Particularly for recurrent or advanced cases.
• Appendiceal Cancer: Including mucinous adenocarcinoma.
• Peritoneal Mesothelioma: A rare cancer associated with asbestos exposure.
• Colorectal Cancer: Particularly when there is peritoneal carcinomatosis (cancer spread to the peritoneum).

Risks and Considerations:

• Surgical Risks: As with any major surgery, there are risks of infection, bleeding, and complications from anesthesia.
• Chemotherapy Side Effects: Patients may experience side effects from the chemotherapy drugs, including nausea, fatigue, and potential organ damage, though these are generally localized to the peritoneum.
• Heat-Related Risks: The use of heat can cause damage to healthy tissues and organs within the abdominal cavity.
• Not Suitable for All Patients: HIPEC is not suitable for every patient or every type of cancer. The decision to use HIPEC depends on various factors, including the extent of disease, overall health, and the potential benefits versus risks.